It’s about the size of a credit card and contains nothing but several microfluidic channels which connect to a 3D chamber where segments of human organs are grown and subjected to a multitude of tests that have historically only been carried out in vitro or using animal models: this is the Organ-on-Chip technology being developed at Nortis. CEO of the company, Dr. Thomas Neumann, joins the podcast to discuss the ins and outs of the science behind this technology, as well as the benefits of testing on human tissues directly as opposed to animal models, how the Organ-on-Chip technology allows them to zoom in on particular functions of complex organs like kidneys and livers in a way that would be impossible with the model of an entire organ, how the technology allows for the modeling of diseases such as polycystic kidney disease, the tracking of drug pathways in the body and measurements of drug secretion, and the variety of tissue-engineered structures they’re creating.
Dr. Neumann discusses how this technology could advance personalized medicine and the development of drugs for the treatment of cancer, as well as the potential it holds in the near and long-term future.
Interested in learning more? Tune in and visit https://www.nortisbio.com/.