Chief Academic Officer at Beth Israel Lahey Health, Dr. Gyongyi Szabo, joins the show to discuss her research on the role of inflammation in innate immunity and liver disease.
In this episode, you will learn:
For nearly 20 years, Dr. Szabo has been studying innate immunity, innate cell function, and signal transduction pathways.
The focus in her lab is on various types of liver diseases that have an inflammatory component, which accounts for almost all liver injuries and chronic liver diseases.
The goal of her research is to gain a better understanding of what causes the inflammatory response in certain liver diseases with the hopes of intervening with certain medications or treatments that would benefit patients suffering from liver disease.
She discusses the difference between innate and adaptive responses of the immune system, how the evolutionary-preserved pattern-recognition receptors that are normally activated by pathogens can also recognize damage-associated molecular patterns, thus leading to low-level systemic inflammation, in what ways her research might lead to an effective treatment for alcohol-related liver disease, and more.